Abstract: Objective:To investigate the risk factors and preventive measures of postmenopausal osteoporosis(PMOP).Methods:The bone density of lumbar spine and hip in 176 patients diagnosed by PMOP were measured.The age,height,weight,duration of menopause,fertility and movement in all cases were analyzed.The influencing factors were investigated using backward iteration method.The ordinal logistic model was established using the reduction of bone mineral density as the dependent variable.The examining factors were substituted into the model,the relationship between the related factor and PMOP was analyzed,and the relevant preventive measures were explored.Results:The age,weight,duration of menopause,fertility,eating habits,present exercise habits,young exercise habits had significant explanatory power on the dependent variable.The age,duration of menopause and fertility were positively correlated to the bone reduce,and risk factors of disease.The body weight,diet,present movement and youth movement were negatively correlated with the bone reduction,and protective factors of disease.Conclusions:Improving the diet structure,increasing the weight and fat content and effective planning the daily movement of PMOP patients can effectively reduce the falling speed of bone mineral density,and control the incidence of PMOP.