Abstract: Objective:To detect the hemodynamics of tortuosity of vertebral artery and congenital vertebral artery variation and value of the Color Doppler Ultrasonography in diagnosis.Methods:The ultrasonic image characteristics in 27 cases of tortuosity and line variation vertebral artery were retrospectively analyzed.The eak systolic flow velocity(PSV) and resistance index(RI) of tortuosity and line variation vertebral artery were measured with ultrasonoraphy to analyze its hemodynamics change patterns.Results:The characteristic ultrasonic image in 16 cases of tortuosity vertebral artery and 11 cases of line variation vertebral artery were found.The PSV in tortuosity vertebral artery group was significantly higher than that in normal control group and contralateral normal group(P<0.01).The PSV in line variation vertebral artery group was significantly higher than that in normal control group(P<0.01).The RI in tortuosity vertebral artery group,contralateral normal group and line variation vertebral artery group were significantly higher than that in normal control group(P<0.05).Conclusions:The ultrasonic images in tortuosity and line variation vertebral artery are characteristic,the diagnostic accurate rate of ultrasonoraphy is high,which can reflect the change of hemodynamics,predict the risk of atherosclerosis plaque forming.