Abstract: Objective:To explore the effects of Jidesheng Sheyao tablet topical concentration on the swelling caused by snakebite,and nursing experience.Methods:Ninety patients with snakebite were randomly divided into the low dose group,medium dose group and high dose group.Three groups were treated with appropriate antivenom,preventing tetanus,anti-infection,anti-fibrinolysis and improving microcirculation.Three groups were additionally treated with low dose,medium dose and high dose of Jidesheng Sheyao tablets,and good nursing,respectively.The clinical efficacy,main symptoms disappearing time and hospitalization time between three groups were compared.Results:After treatment,the total effective rate in low,medium and high dose groups were 63.3%,80.0% and 96.7%,respectively(P<0.05).The local swelling disappearing time,pain disappearing time,wound healing time and hospitalization time in high,medium and low dose groups gradually prolonged in turn(P<0.05 to P<0.01).Conclusions:On the basis of routine treatment and nursing,the different concentrations of Jidesheng Sheyao tablets can effectively alleviate the external swelling of snakebite,and the better clinical efficacy,the higher dose of tablet we will porate patients.