Abstract: Objective:To investigate the clinical value of hyperbaric oxygen in the treatment of viral encephalitis in children.Methods:Forty-six children with viral meningitis were randomly divided into the control group and observation group(23 cases each group).The control group and observation group were treated with routine method and hyperbaric oxygen based on routine method,respectively.The serum indicators related to neural function in two groups before treatment and 10 d,20 d and 30 d after treatment were detected,and the results of whose between two groups were compared.Results:The differences of the serum indicators related to neural function,peripheral blood T lymphocyte subsets and cerebral oxygen metabolism index between two groups before treatment were not statistically significant(P>0.05).After treatment,these indicators were improved to a certain degree(P<0.05 to P<0.01),and the results of indicators after 10 d,20 d and 30 d of treatment in observation group were better than those in control group(P<0.05).Conclusions:The clinical value of hyperbaric oxygen in the treatment of viral encephalitis is high,which can positively improve the neural function,immune function and cerebral oxygen metabolism of children.