Abstract: Objective:To investigate the value of high-frequency ultrasound in the diagnosis of glomus tumor.Methods:The clinical and ultrasound characteristics in 15 cases with glomus tumor were retrospectively analyzed,which was compared with 45 cases with neurinomas and 14 cases with angioleiomyoma.Results:The differences of the age and gender of patients,distribution,long diameter,front and back diameter of tumor,and pain of patients among the glomus tumor,neurinomas and angioleiomyoma were statistically significant(P<0.05 to P<0.01).More common in young women,small lesions,main distributing in the digital toes and often accompanied by characteristic pain were the clinical features of glomus tumor compared with neurinomas and angioleiomyoma.The differences of echo uniformity and doppler flow signals under ultrasound among the glomus tumor,neurinomas and angioleiomyoma were not statistically significant(P>0.05).Conclusions:Glomus tumor has characteristically clinical and ultrasonic features,and high-frequency ultrasound can be set as the preferred inspection method of glomus tumor.