Abstract: Objective:To explore and practice the reserch experimental teaching of molecular diagnostics based on the cultivation of innovative talents.Methods:The research experimental teaching of molecular diagnostics was carried out in grade 2014 students of medical test technology(observation group),and the traditional teaching method was implemented in grade 2013 students of medical test technology(control group).The teaching effect between two groups was compared.Results:The autonomous learning ability,creative thinking ability,team cooperation ability,literature review ability and training of paper writing ability in observation groups were obviously better than those in control group(P<0.01).Conclusions:Compared with the traditional teaching,the research experimental teaching model can improve the autonomous learning ability,practical application ability and creative thinking ability,which is more conducive to the cultivation of innovative and practical test technicians.