ObjectiveTo investigate the diagnostic value of intrapapillary capillary loop(IPCL) classification in early esophageal cancer.

MethodsOne hundred patients suspected by early esophageal tumors under esophagogastroscopy were randomly divided into the IPCL group and Lugol's group(50 cases each group).After the esophagus in all patients were detected using routine white-light endoscopy, the Lugol's group was detected using the routine iodine staining, and the IPCL group was detected using the endoscopic narrow band imaying combined with magnifying endoscopy.The clarity of lesion tissue in two groups was evaluated, the IPCL classification of lesion tissue was compared with the results of histopathological examination, and the sensitivity and specificity of IPCL classification to early esophageal tumor were evaluated.

ResultsThe difference of the clarity of lesion tissue between two groups was not statistically significant(P>0.05), and the differences of the diagnostic coincidence rate, sensitivity to early esophageal cancer and positive predictive value between two groups were statistically significant(P < 0.05~P < 0.01).The difference of the specificity between two groups was not statistically significant(P>0.05).The accuracy rate of the IPCL classification in the judgement of the depth of invasion of early esophageal cancer was 70.83%.

ConclusionsIPCL classification can accurately judge the nature and depth of invasion of esophageal lesion, improve the diagnostic rate of early esophageal tumors, and has important guiding significance for clinical treatment.