陈花花, 陈雷, 齐爱琴, 虞佳其. NPWT联合银离子水凝胶敷料治疗糖尿病足溃疡疗效观察[J]. 蚌埠医学院学报, 2019, 44(9): 1213-1216. DOI: 10.13898/j.cnki.issn.1000-2200.2019.09.019
    引用本文: 陈花花, 陈雷, 齐爱琴, 虞佳其. NPWT联合银离子水凝胶敷料治疗糖尿病足溃疡疗效观察[J]. 蚌埠医学院学报, 2019, 44(9): 1213-1216. DOI: 10.13898/j.cnki.issn.1000-2200.2019.09.019
    CHEN Hua-hua, CHEN Lei, QI Ai-qin, YU Jia-qi. Clinical observation of NPWT combined with silver ion hydrogel dressing in the treatment of diabetic foot ulcer[J]. Journal of Bengbu Medical College, 2019, 44(9): 1213-1216. DOI: 10.13898/j.cnki.issn.1000-2200.2019.09.019
    Citation: CHEN Hua-hua, CHEN Lei, QI Ai-qin, YU Jia-qi. Clinical observation of NPWT combined with silver ion hydrogel dressing in the treatment of diabetic foot ulcer[J]. Journal of Bengbu Medical College, 2019, 44(9): 1213-1216. DOI: 10.13898/j.cnki.issn.1000-2200.2019.09.019

    NPWT联合银离子水凝胶敷料治疗糖尿病足溃疡疗效观察

    Clinical observation of NPWT combined with silver ion hydrogel dressing in the treatment of diabetic foot ulcer

    • 摘要:
      目的探究负压创面治疗(negative pressure wound therapy,NPWT)联合银离子水凝胶敷料在糖尿病足溃疡治疗中的效果。
      方法选取101例糖尿病足溃疡病人,随机分为银离子水凝胶敷料组(A组)、NPWT组(B组)以及NPWT和银离子水凝胶敷料联合组(C组)。比较3组前3周创面肉芽生长积分、创面愈合时间、抗生素使用时间、每人次换药时间以及每人次换药费用。
      结果3组病人创面愈合时间A组最长,B组次之,C组最短(P < 0.05~P < 0.01);抗生素使用时间C组短于A组和B组(P < 0.05~P < 0.01),A组和B组差异无统计学意义(P>0.05)。3组病人第1周肉芽生长积分差异无统计学意义(P>0.05);第2周、第3周A组和B组、B组和C组差异无统计学意义(P>0.05),C组积分低于A组(P < 0.05和P < 0.01)。3组病人换药次数和每人次换药时间,B组和C组均明显短于A组(P < 0.01),B组和C组差异无统计学意义(P>0.05)。3组病人每人次换药费用比较,A组和B组、B组和C组差异均无统计学意义(P>0.05),A组高于C组(P < 0.05)。
      结论NPWT联合银离子水凝胶敷料可以促进肉芽组织生长,缩短糖尿病足溃疡创面的愈合时间,减少抗生素使用时间,未增加医护人员工作量以及治疗费用。

       

      Abstract:
      ObjectiveTo explore the effects of negative pressure wound therapy(NPWT) combined with silver ion hydrogel dressing in the treatment of diabetic foot ulcer.
      MethodsOne hundred and one patients with diabetic foot ulcer were randomly divided into the silver ion hydrogel dressing group(group A), NPWT group(group B) and NPWT combined with silver ion hydrogel dressing(group C).The wound granulation growth integral, wound healing time, antibiotic use time, and time and cost of each change were compared among three groups.
      ResultsThe wound healing time in group A, B and C gradually shortened(P < 0.05 to P < 0.01).The duration of antibiotic use in group C was shorter than that in group A and group B(P < 0.05 to P < 0.01), and the difference of which between group A and group B was not statistically significant(P>0.05).The differences of granulation growth integral among three groups at the first week were not statistically significant(P>0.05), the differences of granulation growth integral between group A and group B, and between group B and group C at the second and third week were not statistically significant(P>0.05), and the granulation growth integral in group C was lower than that in group A(P < 0.05 to P < 0.01).The time and number of dressing change in group B and group C were significantly lower than those in group A(P < 0.01), and the difference of which between group B and group C was not statistically significant(P>0.05).The differences of the cost of dressing change between group A and group B, and between group B and group C were not statistically significant(P>0.05), and the cost of dressing change in group A was higher than that in group C(P < 0.05).
      ConclusionsNPWT combined with silver ion hydrogel dressing can promote the growth of granulation tissue, shorten the healing time of diabetic foot ulcer wound, reduce the use time of antibiotics, and do not increase the workload of medical staff and treatment cost.

       

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