谭慧玲, 王馨, 林见敏, 叶开友, 龚莉华. 上海市郊白鹤镇糖尿病病人视网膜病变患病率及危险因素分析[J]. 蚌埠医学院学报, 2020, 45(1): 89-93. DOI: 10.13898/j.cnki.issn.1000-2200.2020.01.023
    引用本文: 谭慧玲, 王馨, 林见敏, 叶开友, 龚莉华. 上海市郊白鹤镇糖尿病病人视网膜病变患病率及危险因素分析[J]. 蚌埠医学院学报, 2020, 45(1): 89-93. DOI: 10.13898/j.cnki.issn.1000-2200.2020.01.023
    TAN Hui-ling, WANG Xin, LIN Jian-min, YE Kai-you, GONG Li-hua. Analysis of the prevalence and risk factors of retinopathy in diabetic patients in a suburb of Shanghai[J]. Journal of Bengbu Medical College, 2020, 45(1): 89-93. DOI: 10.13898/j.cnki.issn.1000-2200.2020.01.023
    Citation: TAN Hui-ling, WANG Xin, LIN Jian-min, YE Kai-you, GONG Li-hua. Analysis of the prevalence and risk factors of retinopathy in diabetic patients in a suburb of Shanghai[J]. Journal of Bengbu Medical College, 2020, 45(1): 89-93. DOI: 10.13898/j.cnki.issn.1000-2200.2020.01.023

    上海市郊白鹤镇糖尿病病人视网膜病变患病率及危险因素分析

    Analysis of the prevalence and risk factors of retinopathy in diabetic patients in a suburb of Shanghai

    • 摘要:
      目的调查上海市郊白鹤镇糖尿病(diabetic mellitus,DM)病人糖尿病视网膜病变(diabetic retinopathy,DR)的患病情况,并进行患病率及危险因素分析。
      方法采用以人群为基础的横断面研究。于2017年7月,从白鹤镇疾控中心居民健康档案中获取889名DM居民登记信息,收集该人群血液、尿液样本,同时进行眼底照相获取DR信息。以2002年DR国际临床分级标准对眼底照片进行判读。
      结果实际受检822人,应答率92.46%,其中眼底照片可判读者743例,占90.4%。共检出DR病人115例,患病率15.5%,其中轻度非增殖性DR(nonproliferative DR,NPDR)、中度NPDR、重度NPDR以及增殖性DR分别占26.09%、52.17%、14.78%、6.96%;多变量logistic回归分析显示空腹血糖高、糖化血红蛋白高、尿肌酐低是DR的独立危险因素(P < 0.05~P < 0.01);糖尿病黄斑水肿(diabetic macular edema,DME)病人19例,患病率2.56%。DME分布与DR分级存在关联,DME出现频率随DR严重程度发展增加(P < 0.01)。
      结论上海市郊白鹤镇DM病人DR患病率为15.5%,以NPDR为主,即尚处病程前期,故应及时采取相应诊断和干预,防控DR发展。

       

      Abstract:
      ObjectiveTo investigate the prevalence and risk factors of diabetic retinopathy (DR) in patients with diabetic mellitus (DM) in a suburb of Shanghai.
      MethodsA population-based cross-sectional study was used.In July 2017, the registration information of 889 DM residents were obtained from the resident health archives of Baihe Center for Disease Prevention and Control.The information of blood and urine samples were analyzed, and the DR information was collected using the fundus images in all cases.The fundus images were analyzed according to the 2002 DR international clinical grading standard.
      ResultsThe response rate in 698 residents was 92.46%, and 743 cases (90.4%) were diagnosed by fundus images.A total of 115 DR patients were diagnosed, and the prevalence of DR was 15.5%.Among them, the mild nonproliferative DR (NPDR), moderate NPDR, severe NPDR and proliferative DR accounted for 26.09%, 52.17%, 14.78% and 6.96%, respectively.The results of multivariate logistic regression analysis showed that the high fasting blood glucose, high glycosylated hemoglobin, and low urine creatinine were the independent risk factors of DR (P < 0.05 to P < 0.01).The diabetic macular edema (DME) in 19 patients was found, and the prevalence of which was 2.56%.The DME distribution was associated with the DR grading, and the frequency of DME increased with the increasing of DR severity (P < 0.01).
      ConclusionsThe prevalence of DR in DM patients in Baihe town, a suburb of Shanghai, is 15.5%.The NPDR is the main, and still in the early stage of the disease.Therefore, the diagnosis and intervention should timely be taken to prevent and control the development of DR.

       

    /

    返回文章
    返回