脑白质疏松症的经颅多普勒超声研究

潘攀; 杨晶

doi:10.13898/j.cnki.issn.1000-2200.2020.04.021

脑白质疏松症的经颅多普勒超声研究

潘攀,
杨晶

Study on transcranial doppler in patients with leukoaraiosis

PAN Pan,
YANG Jing

摘要

摘要:
目的应用经颅多普勒超声（TCD）研究脑白质疏松症（LA）的血流动力学变化。
方法受试者（LA组）102例为LA病人（脑MRI证实），对照组为96例无LA的正常老人。LA组再依据Fazkas量表进行不同病变程度分组。所有研究对象均行TCD检查，记录双侧大脑中动脉（MCA）、大脑前动脉（ACA）、颈内动脉（ICA）、大脑后动脉（PCA）、椎动脉（VA）及基底动脉（BSA）的血流速度（Vm）及搏动指数（PI）。
结果LA组MCA、ICA、ACA的Vm值较对照组减慢（P < 0.05~P < 0.01），PI值升高（P < 0.05~P < 0.01）。LA组随着病变程度的增加，Vm值逐渐降低（P < 0.05~P < 0.01），PI值逐渐升高（P < 0.05~P < 0.01）。
结论脑白质区域的血液主要由颈内系统提供，LA病人的脑血流速度减少，血流阻力升高；随着LA病变程度的改变，脑灌注逐渐下降。

Abstract:
ObjectiveTo observe the changes of the cerebral blooding flow in patients with leukoaraiosis(LA) using transcranial doppler(TCD).
MethodsOne hundred and two LA patients diagnosed by MRI and 96 normal elders were divided into the LA group and control group, respectively.The LA group was furtherly divided into group according to different lesion degree by Fazkas scale analysis.All cases were examined using TCD, and the flow velocity(Vm) and pulse index(PI) of the bilateral middle cerebral artery(MCA), anterior cerebral artery(ACA), internal carotid artery(ICA), posterior cerebral artery(PCA), vertebral artery(VA) and basilar artery(BSA) was recorded.
ResultsCompared with the control group, the Vm and PI of MCA, ICA, ACA in LA group slowed down and increased, respectively(P < 0.05 to P < 0.01).With the increasing of lesion degree in LA group, the Vm value decreased gradually, and the PI value increased gradually(P < 0.05 to P < 0.01).
ConclusionsThe blood in the white matter area of brain is mainly supplied by the internal system of neck, the cerebral flow decreases, and the cerebral vascular resistance increases in LA patients.With the LA degree increasing, the cerebral perfusion decreases.

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