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    刘传苗, 徐鹤, 李淑华, 赵灿灿, 李小虎, 王健, 赵伟, 施彪, 谢宗玉. 不同年龄段新型冠状病毒肺炎的临床和CT影像特征分析[J]. 蚌埠医科大学学报, 2020, 45(9): 1173-1177. DOI: 10.13898/j.cnki.issn.1000-2200.2020.09.008
    引用本文: 刘传苗, 徐鹤, 李淑华, 赵灿灿, 李小虎, 王健, 赵伟, 施彪, 谢宗玉. 不同年龄段新型冠状病毒肺炎的临床和CT影像特征分析[J]. 蚌埠医科大学学报, 2020, 45(9): 1173-1177. DOI: 10.13898/j.cnki.issn.1000-2200.2020.09.008
    shu
    LIU Chuan-miao, XU He, LI Shu-hua, ZHAO Can-can, LI Xiao-hu, WANG Jian, ZHAO Wei, SHI Biao, XIE Zong-yu. Clinical and CT findings of coronavirus disease 2019 in the different age groups[J]. Journal of Bengbu Medical University, 2020, 45(9): 1173-1177. DOI: 10.13898/j.cnki.issn.1000-2200.2020.09.008
    Citation: LIU Chuan-miao, XU He, LI Shu-hua, ZHAO Can-can, LI Xiao-hu, WANG Jian, ZHAO Wei, SHI Biao, XIE Zong-yu. Clinical and CT findings of coronavirus disease 2019 in the different age groups[J]. Journal of Bengbu Medical University, 2020, 45(9): 1173-1177. DOI: 10.13898/j.cnki.issn.1000-2200.2020.09.008
    shu

    不同年龄段新型冠状病毒肺炎的临床和CT影像特征分析

    Clinical and CT findings of coronavirus disease 2019 in the different age groups

      摘要
    • 摘要:
      目的分析不同年龄组间新型冠状病毒肺炎（coronavirus disease 2019，COVID-19）临床和CT影像特征的差异性。
      方法回顾性分析107例经临床证实COVID-19病人的临床和CT资料，依据不同年龄段分为3组（< 30岁组，30~60岁组，>60岁组），对每组病人CT特点及临床资料进行分析。
      结果107例COVID-19的典型临床表现为发热（98.1%，105/107）和咳嗽（77.6%，83/107），实验室检查C反应蛋白升高（63.6%，68/107），白细胞和淋巴细胞减低（42.1%，45/107；43.9%，47/107）；典型CT表现为两肺多叶散在的胸膜下磨玻璃影（94.4%，101/107），最常伴有血管扩张（89.7%，96/107）和晕征（78.5，84/107）。呼吸困难和临床分型在 < 30岁组、>60岁组和30~60岁组、>60岁组之间差异有统计学意义（P < 0.05）。3组间的肺叶分布差异最为明显（P < 0.05）。铺路石征和实性成分在>60岁组和 < 30岁组、30~60岁组之间差异有统计学意义（P < 0.05）。
      结论COVID-19的临床表现、实验室检查和CT表现具有一定特征性，但不同年龄组间又各具特点，掌握这些临床和CT影像特征、特点有助于早期明确诊断。

       

      Abstract:
      ObjectiveTo analyze the differences of the clinical and CT imaging features of coronavirus disease 2019 (COVID-19) in the different age groups.
      MethodsThe clinical and CT data of 107 patients with clinically confirmed covid-19 were retrospectively analyzed and divided into three groups (< 30 years old group, 30-60 years old group, and >60 years old group) according to their ages.The CT findings and clinical data were analyzed in three groups.
      ResultsThe typical clinical symptoms of COVID-19 in 107 patients showed fever (98.1%, 105/107) and cough (77.6%, 83/107).Laboratory examination showed increased C-reactive protein (63.6%, 68/107), and decreased white blood cells and lymphocytes (42.1%, 45/107;43.9%, 47/107).The typical CT findings displayed scattered subpleural ground-glass opacity in two lungs (94.4%, 101/107), most commonly accompanied with vasodilation (89.7%, 96/107) and halo sign (78.5%, 84/107).Dyspnea and clinical type were statistically significant between < 30 years old group, >60 years old group and 30-60 years old group, >60 years old group (P < 0.05).The difference of distribution of lung lobes in three groups was significant (P < 0.05).There were significant differences in paving stone sign and solid components between >60 years old group, < 30 years old group and 30-60 years old group (P < 0.05).
      ConclusionsThe clinical manifestations, laboratory examination and CT findings of COVID-19 have some characteristics, but different age groups possess their own characteristics.Grasping characteristics of these clinical and CT imaging features is helpful for early definite diagnosis.

       

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