内脏脂肪面积、血清胱抑素C与2型糖尿病颈动脉硬化的关系

汪琼; 金国玺; 裴晓艳; 于磊; 汪丽; 胡红艳; 吴凤

doi:10.13898/j.cnki.issn.1000-2200.2021.08.003

内脏脂肪面积、血清胱抑素C与2型糖尿病颈动脉硬化的关系

Study on the correlation of visceral fat area, serum cystatin C with carotid arteriosclerosis in type 2 diabetes mellitus

摘要

摘要:
目的探讨内脏脂肪面积、血清胱抑素C与2型糖尿病颈动脉硬化的相关性。
方法选择2型糖尿病病人127例，根据是否发生颈动脉粥样硬化分为单纯2型糖尿病组（对照组）40例和2型糖尿病合并颈动脉硬化组（硬化组）87例，检测内脏脂肪面积、血清胱抑素C及其他指标，分析内脏脂肪面积、血清胱抑素C与2型糖尿病颈动脉硬化的相关性。
结果单因素分析显示，硬化组年龄、体质量指数、收缩压、病程、胱抑素C、内脂肪面积均大于对照组（P < 0.05~P < 0.01）；logistic回归分析显示，胱抑素C、内脏脂肪面积、年龄是2型糖尿病病人发生颈动脉硬化的危险因素。
结论胱抑素C和内脏脂肪面积与2型糖尿病颈动脉硬化有关，可为2型糖尿病颈动脉硬化的早期诊断提供参考。

Abstract:
ObjectiveTo explore the correlation of visceral fat area and serum cystatin C with carotid atherosclerosis in type 2 diabetes mellitus.
MethodsAccording to whether having carotid artery aterosclerosis, 127 patients with type 2 diabetes mellitus were divided into the simple diabetes mellitus group(control group, 40 cases) and type 2 diabetes mellitus complicated with carotid atherosclerosis(sclerosis group, 87 cases).The visceral fat area, serum cystatin C and other indexes were detected, and the correlation of visceral fat area and serum cystatin C with carotid atherosclerosisin type 2 diabetes mellitus were analyzed.
ResultsThe age, body mass index, systolic blood pressure, course of disease, cystatin C and visceral fat area in sclerosis group were greater than those in control group(P < 0.05 to P < 0.01).The results of logistic regression analysis showed that the cystatin C, visceral fat area and age were the risk factors of carotid atherosclerosis in patients with type 2 diabetes mellitus.
ConclusionsThe cystatin C and visceral fat area are related to the carotid atherosclerosis in type 2 diabetes mellitus, which may provide a reference for early diagnosis of carotid atherosclerosis in type 2 diabetes mellitus.

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