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    丁绍慧. 改良鼻丘径路额窦鼻内镜修正手术治疗难治性鼻-鼻窦炎病人的短期临床研究[J]. 蚌埠医科大学学报, 2021, 46(10): 1447-1450. DOI: 10.13898/j.cnki.issn.1000-2200.2021.10.031
    引用本文: 丁绍慧. 改良鼻丘径路额窦鼻内镜修正手术治疗难治性鼻-鼻窦炎病人的短期临床研究[J]. 蚌埠医科大学学报, 2021, 46(10): 1447-1450. DOI: 10.13898/j.cnki.issn.1000-2200.2021.10.031
    shu
    DING Shao-hui. Study on the short-term effects of modified frontal sinus endoscopic surgery in the treatment of refractory rhinosinusitis[J]. Journal of Bengbu Medical University, 2021, 46(10): 1447-1450. DOI: 10.13898/j.cnki.issn.1000-2200.2021.10.031
    Citation: DING Shao-hui. Study on the short-term effects of modified frontal sinus endoscopic surgery in the treatment of refractory rhinosinusitis[J]. Journal of Bengbu Medical University, 2021, 46(10): 1447-1450. DOI: 10.13898/j.cnki.issn.1000-2200.2021.10.031
    shu

    改良鼻丘径路额窦鼻内镜修正手术治疗难治性鼻-鼻窦炎病人的短期临床研究

    Study on the short-term effects of modified frontal sinus endoscopic surgery in the treatment of refractory rhinosinusitis

      摘要
    • 摘要:
      目的探讨改良鼻丘径路额窦鼻内镜修正手术治疗难治性鼻-鼻窦炎病人的短期疗效。
      方法选取78例难治性鼻-鼻窦炎病人，依据随机数表法分为对照组与观察组，各39例。对照组行鼻窦开放手术，观察组行改良鼻丘径路额窦鼻内镜修正手术。2组均随访3个月，统计对比2组治疗效果、并发症发生率、复发率及手术前后嗅觉功能、鼻黏膜纤毛传输速率、生活质量。
      结果观察组治疗疗效显著高于对照组（P < 0.01）；嗅觉等级优于对照组（P < 0.05）；术后3个月，2组鼻黏膜纤毛传输速率均较术前有所提高（P < 0.01），且观察组显著高于对照组（P < 0.01）；观察组术后并发症发生率7.69%、复发率2.56%均较对照组的25.64%、20.51%低（P < 0.05）；术后2组精神功能及躯体功能症状均较术前显著改善（P < 0.01），且观察组改善情况较对照更明显（P < 0.01）。
      结论对难治性鼻-鼻窦炎病人行改良鼻丘径路额窦鼻内镜修正手术治疗，可有效提高鼻黏膜纤毛传输速率，显著改善病人嗅觉功能及生活质量，且安全性较高，不易复发。

       

      Abstract:
      ObjectiveTo investigate the short-term efficacy of modified frontal sinus endoscopic surgery in the treatment of refractory rhinosinusitis.
      MethodsSeventy-eight patients with refractory rhinosinusitis were divided into the control group and observation group according to the random number table method(39 cases in each group).The control group was treated with sinus open surgery, and the observation group was treated with the modified frontal sinus endoscopic surgery.Two groups were followed up for 3 months.The incidence rate of complication, recurrence rate, olfactory function before and after operation, nasal mucosa ciliary transport rate and quality of life were compared between two groups.
      ResultsThe total effective rate in observation group was significantly higher than that in control group(P < 0.01).The smell level in observation group was significantly better than that in control group(P < 0.05).After 3 months of operation, the nasal mucosa ciliary transport rates in two groups increased compared with before operation(P < 0.01), and which in observation group was significantly higher than that in control group(P < 0.01).The incidence rate of postoperative complications and recurrence rate in observation group(7.69% and 2.56%) were lower than those in control group(25.64% and 20.51%), respectively(P < 0.05).The symptoms of mental function and physical function in two groups after operation were significantly improved compared with those before operation(P < 0.01), and the improvement in observation group was more obvious than that in the control group(P < 0.01).
      ConclusionsThe modified frontal sinus endoscopic surgery in the treatment of refractory rhinosinusitis can effectively improve the nasal mucociliary transmission rate, significantly improve the patient's olfactory function and quality of life, and is high safety and not easy to relapse.

       

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