ObjectiveTo evaluate the effects of clinical pharmacist intervention to optimize insulin use in patients with type 2 diabetes mellitus.

MethodsA total of 136 type 2 diabetes mellitus(T2DM) patients treated with subcutaneous insulin were divided into the control group(68 cases) and observation group(68 cases) according to the random number table method.The control group was treated with the traditional health education, and the observation group was treated with the clinical pharmacists to participate in the guidance of insulin medication for 3 months.The differences of the cognitive level of insulin use, insulin preservation and compliance, blood glucose level and problems in the course of medication were compared between two groups before and after intervention.

ResultsThe name, type and preservation method of insulin, needle specification, precautions before injection, injection method, precautions during injection, needle use, mealtime, score of hypoglycemia self-help, MMAS-8 score and good compliance rate of insulin use in observation group were higher than those in control group(P < 0.01).After intervention, the levels of fasting blood glucose, 2 h postprandial blood glucose and HbA1c in observation group were significantly lower than those in control group(P < 0.01), and the C-peptide level in observation group was significantly higher than that in control group(P < 0.01).During the study period, the incidence rates of fear of insulin injection, hypoglycemia, abnormal skin at the injection site, pain during injection and tip leakage in observation group were lower than those in control group(P < 0.05 to P < 0.01).

ConclusionsThe participation of clinical pharmacists in the guidance of insulin use in elderly diabetic patients can improve the cognitive level of insulin use and medication compliance, maintain the stability of blood glucose level, and improve medication safety.