非特异性下腰痛的影响因素及与血脂代谢异常的关系

王喜; 范金鹏; 康玉芳; 庞文文

doi:10.13898/j.cnki.issn.1000-2200.2021.11.017

非特异性下腰痛的影响因素及与血脂代谢异常的关系

Study on the influencing factors of nonspecific low back pain and its relationship with dyslipidemia

摘要

摘要:
目的探讨非特异性下腰痛（nonspecific low back pain，NLBP）的影响因素及与血脂代谢异常的关系。
方法回顾性选取NLBP病人86例为研究对象（观察组），另选取同期健康体检者72名为对照组。收集受试者相关临床资料，分析NLBP的相关影响因素及与血脂代谢的关系。
结果观察组总胆固醇、三酰甘油水平均明显高于对照组（P < 0.01）。单因素分析显示，观察组与对照组职业、是否家庭主要经济来源、工作强度、运动、居住地、高三酰甘油血症、高胆固醇血症和Roland-Morris功能障碍表及生存质量测定简表（WHOQOL-BREF）评分差异均具有统计学意义（P < 0.01），而性别、年龄、体质量指数、受教育程度、婚姻状况、吸烟、饮酒、高血压和糖尿病差异均无统计学意义（P>0.05）。logistic回归分析结果显示，职业、家庭主要经济来源、工作强度、运动、高胆固醇血症及WHOQOL-BREF评分均为NLBP的独立影响因素（P < 0.05~P < 0.01）。
结论职业、家庭主要经济来源、工作强度、运动、高胆固醇血症及WHOQOL-BREF评分等均可影响NLBP的发生，且血脂代谢异常可加重病人腰椎间盘退变，从而增加NLBP的发病风险。

Abstract:
ObjectiveTo explore the influencing factors of nonspecific low back pain(NLBP), and its relationship with dyslipidemia.
MethodsThe clinical data of 86 NLBP patients were retrospectively analyzed, and set as the observation group, and 72 healthy people in the same period were set as the control group.The relevant clinical data of the subjects were collected, and the related influencing factors of NLBP, and relationship between NLBP and lipid metabolism were analyzed.
ResultsThe TC and TG levels in observation group were significantly higher than those in control group(P < 0.01).The results of univariate analysis showed that the differences of the occupation, main source of family income, work intensity, exercise, residence, hypertriglyceridemia and WHOQOL-BREF score between two groups were statistically significant(P < 0.01).The results of logistic regression analysis showed that the occupation, family main source of family income, work intensity, exercise, hyper cholesterolemia and WHOQOL-BREF score were the influencing factors of NLBP(P < 0.05 to P < 0.01).
ConclusionsThe occupation, family main source of income, work intensity, exercise, hypercholesterolemia and WHOQOL-BREF score can affect the occurrence of NLBP, and the abnormal lipid metabolism can aggravate patients' lumbar disc degeneration to increase the risk of NLBP.

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