李姝, 刘浩, 李光荣, 杨明, 朱善良, 莫绪明. 婴幼儿危重型先天性心脏病256层CT低管电压心脏增强扫描中造影剂最小剂量分析[J]. 蚌埠医学院学报, 2021, 46(11): 1600-1603. DOI: 10.13898/j.cnki.issn.1000-2200.2021.11.026
    引用本文: 李姝, 刘浩, 李光荣, 杨明, 朱善良, 莫绪明. 婴幼儿危重型先天性心脏病256层CT低管电压心脏增强扫描中造影剂最小剂量分析[J]. 蚌埠医学院学报, 2021, 46(11): 1600-1603. DOI: 10.13898/j.cnki.issn.1000-2200.2021.11.026
    LI Shu, LIU Hao, LI Guang-rong, YANG Ming, ZHU Shan-liang, MO Xu-ming. Analysis of the minimum dose of contrast media in 256-slice cardiac enhanced iCT scan with low tube voltage in infants with critical congenital heart disease[J]. Journal of Bengbu Medical College, 2021, 46(11): 1600-1603. DOI: 10.13898/j.cnki.issn.1000-2200.2021.11.026
    Citation: LI Shu, LIU Hao, LI Guang-rong, YANG Ming, ZHU Shan-liang, MO Xu-ming. Analysis of the minimum dose of contrast media in 256-slice cardiac enhanced iCT scan with low tube voltage in infants with critical congenital heart disease[J]. Journal of Bengbu Medical College, 2021, 46(11): 1600-1603. DOI: 10.13898/j.cnki.issn.1000-2200.2021.11.026

    婴幼儿危重型先天性心脏病256层CT低管电压心脏增强扫描中造影剂最小剂量分析

    Analysis of the minimum dose of contrast media in 256-slice cardiac enhanced iCT scan with low tube voltage in infants with critical congenital heart disease

    • 摘要:
      目的分析70 kV管电压条件下婴幼儿心脏增强CT扫描中造影剂最小用量。
      方法选取行心脏CT增强扫描的96例危重型先天性心脏病患儿,随机分为A、B、C组,各32例。造影剂选择非离子型碘造影剂(含碘320 mg/mL),A、B、C组患儿造影剂用量分别为1.0、1.5、2.0 mL/kg。另选100例2月龄以内行心脏大血管增强先天性心脏病患儿,随机分为E、F组,各50例,管电压分别为80 kV和100 kV,其他扫描条件不变。观察A、B、C组噪声、信噪比、主观评分、诊断的准确率及左、右心室的CT值、室间隔强化值(ΔHU),比较实验组、E组、F组的辐射剂量,分析室间隔ΔHU与造影剂用量的线性关系。
      结果A、B、C组的主观评分、噪声、信噪比及诊断的准确率差异均无统计学意义(P>0.05);A、B、C组心脏左心室、右心室CT值及室间隔ΔHU逐渐升高,差异有统计学意义(P < 0.05)。E、F组与实验组相比,随着管电压的增加,辐射剂量逐渐增高(P < 0.05)。室间隔ΔHU与造影剂用量的线性回归公式为:ΔHU=89.71+2.3×造影剂剂量,在满足室间隔ΔHU ≥ 100 HU条件下,造影剂最小剂量0.75 mL/kg。
      结论70 kV条件下婴幼儿心脏CT增强扫描所需造影剂最小剂量为0.75 mL/kg。

       

      Abstract:
      ObjectiveTo analyze the minimum dose of contrast media in cardiac enhanced CT scan at 70 kV tube voltage.
      MethodsA total of 96 infants with critical congenital heart disease received cardiac enhanced CT scan were selected and randomly divided into group A, group B and group C (32 cases in each group).Non-ionic iodine contrast media (iodine concentration 320 mg/mL) was used, and the dose of contrast media in group A, B and C was 1.0, 1.5 and 2.0 mL/kg, respectively.Another 100 children less than 2-month old with endocardial macrovascular enhancement were randomly divided into group E and group F (50 cases in each group), with 80 kV and 100 kV tube voltage, respectively, at the same other scanning conditions.The noise, signal-to-noise ratio, subjective score, diagnostic accuracy, CT value of left and right ventricle and enhancement value (ΔHU) of ventricular septal were observed in group A, B and C; the radiation dose in experimental group, group E and F was compared; and the linear relationship between ΔHU of ventricular septum and contrast media dose was analyzed.
      ResultsThere were no significant differences in subjective score, noise, signal-to-noise ratio and diagnostic accuracy among group A, B and C(P>0.05).The CT value of left ventricle and right ventricle and ΔHU of ventricular septum in group A, B and C increased gradually, the difference of which was statistically significant(P < 0.05).Compared with the experimental group, the radiation dose in group E and F increased gradually with the increase of tube voltage(P < 0.05).The linear regression formula between the ΔHU of ventricular septum and the dose of contrast media was: ΔHU=89.71+2.3×dose of contrast media, at the condition of ΔHU of ventricular septum ≥ 100 HU, the minimum dose of contrast media was 0.75 mL/kg.
      ConclusionsThe minimum dose of contrast media for cardiac enhanced CT scan at 70 kV in infants was 0.75 mL/kg.

       

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