ObjectiveTo investigate the effects of platelet-rich fibrin(PRF) in the repair of bone defect around immediate implant teeth.

MethodsA total of 74 patients(86 affected teeth) with obvious labial bone plate thinness or bone defect detected by preoperative cone beam CT(CBCT) and conforming to the indications of immediate dental implant were investigated, and divided randomly into the observation group(37 cases, 45 teeth) and control group(37 cases, 41 teeth).The dental implants in the observation group were treated with the PRF bone graft material, oral repair film and PRF film, and the control group was implanted with bone graft material and oral repair film at the same time.The thickness of the top, middle and apex of labial bone plate in sagittal position in two groups were measured before operation.The NobelReplace Conical Connection was immediately implanted, and the affected teeth in two groups were treated with the above surgical procedures, and the wound surface was tightly sutured.Two groups were examined using CBCT at immediate time after surgery and after 6 months of operation, and the thickness and implant stability quotient (ISQ) of the three parts of the labial bone plate in sagittal implant were measured.

ResultsThe measurement values of the top, middle and apical part of the labial bone plate in two groups at immediate time after surgery and after 6 months of surgery were higher than those before extraction(P < 0.05).The differences of the measurement value of three parts of labial bone plate before and at immediate time after tooth extraction were not statistically significant between the two groups(P>0.05), but after 6 months of surgery, the measured values of the three parts in observation group were higher than those in control group(P < 0.05).The results of intra-group comparison showed that the ISQ values in the two groups after 6 months of surgery were higher than that at immediate time after surgery(P < 0.05).However, there was no statistical significance in the ISQ values at immediate time and after 6 months of surgery between the two groups(P>0.05).

ConclusionsCompared with the traditional repair method, the PRF bone graft material, oral repair film and PRF film can more effectively repair the labial bone defect, which is worthy of clinical promotion.