魏然. 胎儿脐动脉联合大脑中动脉血流动力学在单胎妊娠合并帆状胎盘中的诊断效能评价[J]. 蚌埠医学院学报, 2022, 47(4): 521-524. DOI: 10.13898/j.cnki.issn.1000-2200.2022.04.023
    引用本文: 魏然. 胎儿脐动脉联合大脑中动脉血流动力学在单胎妊娠合并帆状胎盘中的诊断效能评价[J]. 蚌埠医学院学报, 2022, 47(4): 521-524. DOI: 10.13898/j.cnki.issn.1000-2200.2022.04.023
    WEI Ran. Evaluation of the diagnostic efficacy of the fetal umbilical artery combined with middle cerebral artery hemodynamics in single pregnancy complicated with vela placenta[J]. Journal of Bengbu Medical College, 2022, 47(4): 521-524. DOI: 10.13898/j.cnki.issn.1000-2200.2022.04.023
    Citation: WEI Ran. Evaluation of the diagnostic efficacy of the fetal umbilical artery combined with middle cerebral artery hemodynamics in single pregnancy complicated with vela placenta[J]. Journal of Bengbu Medical College, 2022, 47(4): 521-524. DOI: 10.13898/j.cnki.issn.1000-2200.2022.04.023

    胎儿脐动脉联合大脑中动脉血流动力学在单胎妊娠合并帆状胎盘中的诊断效能评价

    Evaluation of the diagnostic efficacy of the fetal umbilical artery combined with middle cerebral artery hemodynamics in single pregnancy complicated with vela placenta

    • 摘要:
      目的探讨胎儿脐动脉(UA)联合大脑中动脉(MCA)血流动力学在单胎妊娠合并帆状胎盘中的诊断效能。
      方法选择2017年11月至2020年11月单胎妊娠者50例,设为对照组;选择同期治疗的单胎妊娠合并帆状胎盘者50例,设为观察组。2组均采用彩色多普勒超声技术检测者UA包括脐动脉收缩期峰值流速/舒张末期流速(S/D)值、阻力指数(RI)及搏动指数(PI)、MCA血流动力学阻力指数(RI)及搏动指数(PI)指标;绘制ROC曲线,分析UA、MCA血流动力学在单胎妊娠合并帆状胎盘中的诊断效能(灵敏度、特异度)。
      结果观察组UA血流动力学中S/D、RI及PI水平均高于对照组(P < 0.01);观察组MCA血流动力学中RI、PI水平均低于对照组(P < 0.01);ROC曲线结果表明:UA联合MCA血流动力学在单胎妊娠合并帆状胎盘中的诊断效能高于单一UA和MCA血流动力学(P < 0.01),灵敏度分别为93.51%、79.43%和84.17%,特异度分别为61.42%、67.81%和65.67%。
      结论UA血流动力学中S/D、RI及PI在单胎妊娠合并帆状胎盘病人中呈高表达,而MCA血流动力学呈低表达,加强胎儿UA及MCA联合测定能获得较高的诊断效能,可指导临床治疗。

       

      Abstract:
      ObjectiveTo investigate the diagnostic efficacy of fetal umbilical artery(UA) combined with middle cerebral artery(MCA) hemodynamics in single pregnancy complicated with vela placenta.
      MethodsFifty cases of single pregnancy women from November 2017 to November 2020 were set as the control group, and 50 pregnancy women with single pregnancy complicated with vela placenta were set as the observation group.The UAincluding peak systolic velocity/end-diastolic velocity(S/D), resistance index(RI) and pulsation index(PI) of umbilical artery, MCA hemodynamics(RI and PI) in two groups were measured using color Doppler ultrasound.The ROC curve was drawn to analyze the diagnostic efficacy(sensitivity and specificity) of UA and MCA hemodynamics in single pregnancy complicated with vela placenta.
      ResultsThe levels of S/D, RI and PI in UA hemodynamics in observation group were higher than those in control group(P < 0.01).The levels of RI and PI in MCA hemodynamics in observation group were lower than those in control group(P < 0.01).The results of ROC curve showed that the diagnostic efficacy of UA combined with MCA hemodynamics in single pregnancy complicated with vela placenta was higher than that of UA or MCA hemodynamics alone(P < 0.01).The sensitivities of single UA or MCA and the combination of UA and MCA were 79.43%, 84.17% and 93.51%, respectively.The specificities of single UA or MCA and two combination of UA and MCA were 67.81%, 65.67% and 61.42%, respectively.
      ConclusionsIn UA hemodynamics, the expression levels of S/D, RI and PI in patients with single pregnancy complicated with vela placenta are high, while the level of MCA hemodynamics is low.Strengthening the combined determination of fetal UA and MCA can obtain the high diagnostic efficacy, which can guide the clinical treatment.

       

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