ObjectiveTo compare the efficacy of drug-coated balloon and common balloon in the treatment of autogenous arteriovenous fistula stenosis.

MethodsA total of 42 patients with arteriovenous fistula stenosis were selected as the subjects.According to the treatment methods, 42 patients were divided into drug-coated balloon group(DCB group)(n=20) and common balloon group(CB group)(n=22).Patients in DCB group were treated with paclitaxel release high pressure shunt balloon dilatation, while the patients in CB group were treated with common balloon dilatation.The success rate of operation, diameter and dialysis blood flow of stenosis before and after operation, primary patency rate of arteriovenous fistula at 1, 6 and 12 months after operation and complications within one month after operation were compared between the two groups.

ResultsThe success rate of operation in both groups was 100%.Before and after operation, the difference of diameter of stenosis and dialysis blood flow between the two groups were not statistically significant(P>0.05).After operation, the internal diameter and dialysis blood flow of the stenosis were significantly improved in the two groups compared with those before operation(P < 0.01), but there was no significant difference between the two groups(P>0.05).At 1 and 12 months after operation, there was no significant difference in the primary patency rate of arteriovenous fistula between the two groups (P>0.05).At 6 months after operation, the primary patency rate in DCB group was higher than that in CB group(P < 0.05).There was no significant difference in the incidence of complications at 1 month after operation between the two groups(P>0.05).

ConclusionsDrug coated balloon angioplasty is superior to common balloon angioplasty in the treatment of autogenous arteriovenous fistula stenosis, which can be used as one of the safe and effective option for the treatment of autogenous arteriovenous fistula stenosis.