ObjectiveTo investigate the efficacy of modified pterygium resection combined with limbal stem cell transplantation in situ suture.

MethodsA total of 100 patients with primary pterygium were selected and divide into observation group and control group according to random number table method, with 50 cases in each group.The control group was treated with conventional pterygium resection combined with limbal stem cell transplantation, and the observation group was treated with pterygium resection combined with limbal stem cell transplantation in situ suture.The corneal wound healing time, conjunctival incision healing time, postoperative pain score, patient's subjective discomfort and recurrence rate were compared between the two groups.

ResultsThe pain scores in the two groups gradually decreased on the day of operation, on the first day, second day, and third day after operation(P < 0.05), and the pain scores in observation group at the above time-points were significantly lower than those in control group(P < 0.01).The corneal wound healing time and conjunctival incision healing time in observation group were significantly shorter than those in control group(P < 0.01).There was no significant difference in tear film rupture time between the two groups before operation(P>0.05), but the tear film rupture time in observation group was significantly shorter than that in control group at one month after operation(P < 0.01).There was no significant difference in the incidence of ocular discomfort at one month after the operation and the recurrence rate at six months after the operation between the two groups(P>0.05).

ConclusionsPterygium resection combined with limbal stem cell transplantation in situ suture covering the conjunctival flap donor area can promote corneal epithelial injury recovery, promote conjunctival incision healing, increase postoperative comfort, and increase the tear film duration in pterygium patients.