ObjectiveTo measure the health utility value of patients with cervical intraepithelial neoplasia and analyze its influencing factors, so as to provide evidence for improving health-related quality of life in this population.

MethodsA total of 125 patients with cervical intraepithelial neoplasia were collected and measured by five-dimension health scale (EQ-5D-5L).Tobit regression model was used to determine the influencing factors.

ResultsThe health utility value of 125 patients with cervical intraepithelial neoplasia was (-0.39, 1), and the mean value was (0.88±0.14).Among the five dimensions, the number of cases with problems was as follows: mobility in 14 cases (11.20%), daily activities in 21 cases (16.80%), self-care in 27 cases (21.60%), anxiety or depression in 80 cases (64.00%), and pain or discomfort in 55 cases (44.00%).There were statistically significant differences in the health effect values of patients with cervical intraepithelial neoplasia in different age groups, marital status, employment status, disease course, disease uncertainty group and general self-efficacy group (P < 0.05 to P < 0.01).Tobit regression model showed that age, disease course, disease uncertainty and general self-efficacy were the factors influencing health utility value (P < 0.05 to P < 0.01).

ConclusionsMore attention should be paid to the psychological status of menopausal and newly diagnosed female patients with cervical intraepithelial neoplasia, and the health-related quality of life should be improved by reducing the uncertainty of the disease and improving the self-efficacy of patients.