Abstract: Objective: To evaluate the clinical efficacy of transvaginal myomectomy. Methods: Of 76 patients with uterine myomas,30 cases were treated by transvaginal myomectomy(group A) and 46 cases by transabdominal myomectomy(group B). The duration of operation,bleeding volume during operation,hospital stay after operation and the time of bowel function recovery were compared between the two groups. Results: The operation was successful in all the cases in group A and no one resorted to transabdominal procedure. Group A were superior to group B in the duration of operation,bleeding volume during operation,hospital stay after operation and the time of bowel function recovery(P < 0.05-P < 0.01). Conclusions: Transvaginal myomectomy has the advantages of minimal invasion and rapid recovery. It is a low invasive and effective procedure for treatment of uterine myomas and is worth popularizing.