Abstract: Objective:To explore the correlation of carotid atherosclerosis and degenerative valvular heart disease through high-frequency ultrasound carotid and echocardiographic examination in elderly patients.Methods:Eighty-eight cases of degenerative valvular heart disease were selected as the study group,49 cases of non-degenerative valvular heart disease as control group,the states of mitral and aortic valve,the internal-middle thickness(IMT) in carotid artery and carotid atherosclerotic plaques were measured and compared in the two groups.Results:The IMT,plaque score,plaque detection rate were higher in study group than in control group(P0.05 to P0.01).In study group,the obliteration rate was 2.27%,the stenosis rate was 90.91%;in control group,there were no luminal occlusion,the stenosis rate was 18.37%,there was no statistical difference of the obliteration rate in the two groups(P=0.573),while the stenosis rate in study group was significantly higher than in control group(P0.01);the complications of coronary heart disease,hypertension,diabetes and hyperlipidemia were significantly higher in study group(P0.01).Conclusions:There are the close relationship between carotid atherosclerosis and degenerative changes in heart valve,the degree of carotid atherosclerosis are increased with the degree of heart valve calcification,carotid atherosclerosis ultrasound should be performed for senile patients with degenerative heart valve disease.