Abstract: Objective: To compare the effect of medical abortion and vacuum suction abortion in terminating early pregnancy,and to study the acceptability and psychological status of the patients.Methods: One hundred and sixty patients intending to terminate pregnancy were divided into medical abortion group and vacuum suction abortion group.The results were compared and analyzed.Results: The complete abortion rate of vacuum suction abortion group(98.75%) was significantly higher than that of medical abortion group(87.50%),and the bleeding time was shorter than that of medical abortion group.The difference was statistically significant(P<0.01).The degree of tension and suffering in the medical abortion group was significantly lighter than that in the vacuum suction abortion group,and the acceptability degree was higher than that of abortion group.The difference was significant(P<0.01).The satisfaction degree of the two groups had no significant difference(P>0.05).Conclusions: Medical abortion and vacuum suction abortion have their own advantages and disadvantages in terminating early pregnancy.The advantages of medical abortion were lighter pain,no tension,higher acceptability degree and satisfaction,the disadvantages were longer vaginal bleeding and longer hospital stay for observation.The advantages of vacuum suction abortion were higher successful rate of abortion and shorter vaginal bleeding,the disadvantages were severe abdominal pain and tension.They are not replaceble.