Abstract: Objective: To investigate the curative effect of sigmoid neobladder after radical cystectomy in 15 patients with invasive bladder cancer. Methods: Sigmoid neobladder was conducted after radical cystectomy in 15 males with bladder cancer. The curative effect and technical points were analyzed. Results: Fifteen cases were followed up for 6 to 72 months. Bilateral and unilateral hydronephrosis was found in 5 cases and in 1 case,respectively. The volume of urodochium was 210 to 456 ml,and the static pressure in neobladder was 18.6 to 31.8 cmH₂O. Vesical micturition pressure was 36.21 to 71.56 cmH₂O. Qmax was between 10.22 to 12.26 ml/s. The residual urine volume was 33 to 58 ml. Daytime incontinence was found in 1 case in the first year after operation. Nocturnal urinary incontinence was found in 11 cases. Conclusions: The sigmoid neobladder had several advantages including an adequate reservoir capacity,recovery of automatic micturition,good renal function,no acid-base and electrolyte imbalance,and the continence effect was good at daytime,but not good at night. It could be a good choice a better operation in replacing bladder.