Abstract: Objective: To observe the clinical curative effect and safety of aerosol inhaled budesonide combined with ambroxol for children with acute laryngitis. Methods: Seventy-one children with acute laryngitis were randomly divided into treatment group and control group. The children in treatment group (32 cases) were cured with aerosol inhalation of budesonide and ambroxol with air compress pump nebuliser,and others in control group(39 cases) were treated with intravenous drip of dexamethasone. Results: The symptoms and signs dispeared significantly faster in the treatment group when compared with that of control group(P < 0.01). The total effective rate of the treatment group was 96.9%,the control group was 74.4% (P < 0.05). Conclusions: The treatment of aerosol inhaled of budesonide combined with ambroxol for children with acute laryngitis has greater efficacy and fewer side effects.