原发性肝癌三维适形放疗35例疗效分析

Three-dimensional conformal radiotherapy for primary hepatocellular carcinoma: Report of 35 cases

摘要: 目的:探讨三维适形放疗治疗原发性肝癌的疗效。方法:采用6 MV X线直线加速器对35例中晚期肝癌进行三维适形放疗。单次剂量2~4 Gy,每天1次,5次/周,总剂量40~62 Gy。结果:完全缓解(CR)率8.6%,部分缓解(PR)率51.4%,稳定率34.3%,进展率8.6%,总有效率(CR+PR)为60.0%。1年生存率为57.1%。结论:三维适形放疗是治疗不能手术的中晚期肝癌的有效途径。

Abstract: Objective: To evaluate the therapeutic efficacy of three-dimensional conformal radiotherapy(3DCRT) on unresectable primary hepatocellular carcinoma.Methods: Thirty-five patients with advanced liver cancer were treated by 3DCRT using 6 MV X-ray.The patients received a total dosage of 40-62 Gy,2-4 Gy per day.Results: Complete remission was detected in 8.6% of the patients,partial remission in 51.4%,no change in 34.3% and progressive disease in 8.6%,with an overall response rate(CR+PR) of 60.0%.One-year survival rate was 57.1%.Conclusions: Three-dimensional conformal radiotherapy is effective for treatment of patients with unrespectable primary hepatocellular carcinoma.