Abstract: Objective:To evaluate the therapeutic efficacy of thrombus aspiration technique and thrombolysis of intracavitary and percutaneous transluminal angioplasty(PTA) for Budd-Chiari syndrome(BCS) complicated with inferior vena cava(IVC)thrombus. Methods:The clinical data of 11 cases of BCS complicated with IVC thrombus were collected.Venipuncture through femoral vein and inferior vena cavography were performed,and aspiration thrombus technique and thrombolysis of intracavitary were used to eliminate thrombus.After angiography of IVC,the recanalization of IVC was performed,which was followed by thrombus aspiration technique and thrombolysis of intracavitary.Finally,IVC was dilated with percutaneous transluminal balloon angioplasty.The clinical observation was used by color Doppler post-discharge. Results:All the patients occlusion was barrier diaphragm before operation,adopting this treatment,7 patients thrombus was eliminated instantly,after using intraductal thrombolysis,2 patients thrombus was eliminated 4 days later,2 patients thrombus was eliminated 7 days later.And pulmonary embolism was not happened with percutaneous transluminal balloon angioplasty.In following-up visit,blood current of IVC was continuous,there had no re-occlusion or thrombus happening. Conclusions:The therapeutic efficacy of thrombus aspiration technique and thrombolysis of intracavitary and PTA for BCS complicated with IVC thrombus is safe and effective.