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    张小鹏, 罗新, 王晓玉. 膜式薄层液基细胞学检查联合初善仪在子宫颈癌前病变诊断中的应用[J]. 蚌埠医科大学学报, 2012, 36(5): 516-518,522.
    引用本文: 张小鹏, 罗新, 王晓玉. 膜式薄层液基细胞学检查联合初善仪在子宫颈癌前病变诊断中的应用[J]. 蚌埠医科大学学报, 2012, 36(5): 516-518,522.
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    ZHANG Xiao-peng, LUO Xin, WANG Xiao-yu. The study of thinprep cytology test combined truscreenin early diagnosis cervical precancerous lesions[J]. Journal of Bengbu Medical University, 2012, 36(5): 516-518,522.
    Citation: ZHANG Xiao-peng, LUO Xin, WANG Xiao-yu. The study of thinprep cytology test combined truscreenin early diagnosis cervical precancerous lesions[J]. Journal of Bengbu Medical University, 2012, 36(5): 516-518,522.
    shu

    膜式薄层液基细胞学检查联合初善仪在子宫颈癌前病变诊断中的应用

    The study of thinprep cytology test combined truscreenin early diagnosis cervical precancerous lesions

      摘要
    • 摘要: 目的：探讨膜式薄层液基细胞学检查(thinprepcytologictest，TCT)联合初善仪(truscreen，TS)在子宫颈癌前病变诊断中的应用价值。方法：对30例阴道分泌物异常的患者同时行TCT和TS检查，再行阴道镜检查及组织活检，以组织病理学检查结果作为诊断的金标准。比较2种检查方法单独及联合使用与组织病理学检查结果的吻合程度。结果：30例患者中有25例病理学诊断为子宫颈上皮内瘤变1级及以上病变，为真阳性。TCT测试细胞学意义不明的不典型鳞状上皮细胞以上的阳性19例(63.3%)，假阴性6例，漏诊率20.0%，真阳性16例，敏感度84.2%。TS测试阳性18例(60.0%)，假阴性7例，漏诊率23.3%，真阳性14例，敏感度77.8%。TCT联合TS测试阳性27例(90.0%)，假阴性1例，漏诊率3.3%，真阳性24例，敏感度88.9%。TCT联合TS检测子宫颈癌前病变的阳性率与病理学检查的阳性率分别为90.0%和83.3%，差异无统计学意义(P0.05)。结论：TCT联合TS检查诊断子宫颈癌前病变的准确性明显优于任一单项检查，其漏诊率显著下降。

       

      Abstract: To investigate the ap lication value of thinprep cytology test(TCT). ombined truscreen(TS)in early diagnosis. ervical precancerous lesions. Methods:Thirty patients with abnormal vaginal secretions were detected under TCT and TS and thenvaginal tissue biopsies were tested under colposcopy. The results of pathological examination acted as the gold standard of diagnosis. Thematch degrees of single and combined using methods and histopathological examination results were compared. Results:The results ofhistopathological examination of 25 cases were cervical intraepithelial neoplasia grade 1 or above. Nineteen cases(63.3% )were ASCUS. ytology positive6 cases were false negativel6 cases were true postivethe rate of fail to diagnosis was 20.0%,and the sensitivenessdegree was 84.2% under TCT. Compared with TCT results the data were 18 cases(60.0% ),7 cases 14 cases23.3% and 77.8% under TS respectively. Compared with TCT or TS results the data were 27 cases(90.0% ),1 case 24 cases 3. 3 % and 88.9 % underTCT and TS respectively. The positive rates of pathology examination and TCT combined with TS inspection was 90.0% and 83.3% respectivelythe difference had not statistical significance(P0. OS). Conclusions: The accuracy of TCT combined with TS inspectionfor diagnosing cervical precancerous lesions is better than any one single examination and its rate of fail to diagnosis declinedsignificantly

       

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