经鼻间歇正压通气治疗新生儿呼吸窘迫综合征的疗效观察

Effects of nasal intermittent positive pressure ventilation in treatment for neonates respiratory distress syndrome

摘要: 目的：观察经鼻间歇正压通气(NIPPV)在新生儿呼吸窘迫综合征(NRDS)中的应用效果。方法：将48例NRDS患儿随机分为NIPPV组(25例)和经鼻持续气道正压通气(NCPAP)组(23例)，观察比较2组治疗的成功率、治疗的时间、治疗前后动脉血气变化、氧合指数及并发症。结果：NIPPV组治疗成功率为72.0%，高于NCPAP组的43.5%(p0.05)，NIPPV组治疗后1h的动脉氧分压、氧合指数的升高显著大于NCPAP组(p0.05)。结论：NIPPV作为初始通气模式治疗NRDS是可行的，且疗效优于NCPAP。

Abstract: To evaluate the effects of nasal intermittent positive pressure ventilation(NIpV)in treatment for neonatesrespiratory distress syndrome(NIDS). Methods: Fortyight neonates with NIDS were randomly divided into NIpV group(25 cases)and nasal continuous positive airway pressure(NCPAP)group(23 cases).