间断与持续鼻饲喂养对极低出生体重儿喂养耐受性和胃泌素水平的影响

Effects of intermittent bolus gavage and continuous nasogastric gavageon the feeding tolerance and gastrin level in very low birth weight infants

摘要: 目的：探讨间断鼻饲喂养(intermittentbolusgavage，IBG)和持续鼻饲喂养(continuousnasogastricgavage，CNG)对极低出生体重儿(verylowbirthweightinfants，VLBWI)喂养耐受性和胃泌素水平的影响。方法：对70例VLBWI行部分胃肠外营养，在此基础上随机分为IBG组(35例)和CNG组(35例)，观察2组达到完全胃肠内喂养所需时间，比较2组患儿喂养第1天和第10天血液中胃泌素水平，并分析2种喂养方式对VLBWI喂养耐受性的影响。结果：IBG组喂养不耐受性发生率较CNG组低(p0.05)，达到完全胃肠内营养时间较CNG组明显缩短(p0.01)；喂养第1天2组胃泌素水平差异无统计学意义(P0.05)，喂养第10天IBG组较CNG组血液中胃泌素水平显著增高(p0.01)。结论：IBG喂养方式对VLBWI喂养耐受性好，且能提高胃泌素分泌水平。

Abstract: To explore the effects of intermittent bolus gavage(IBC)and continuous nasogastric gavage(CNG)on thefeeding tolerance and gastrin level in very low birth weight infants(VLBWI). Methods:Seventy cases of VLBWI who were fed on partialparenteral nutrition were randomly divided into IBC feeding group and CNG feeding group. The time of reaching full enteral feeding(FEF)of both groups was observed. The gastrin level of two groups was compared on the first day and the tenth dayand the elfects ofthe two feeding patterns on the intolerance of VLBWI was analyzed.