急性重度光气中毒患者最佳呼气末正压的应用

Application of the positive end-expiratory pressure mechanical ventilation in acute phosgene poisoning

摘要: 目的:探讨呼气末正压(PEEP)在急性重度光气中毒中的合理应用。方法:对7例急性重度光气中毒患者不同PEEP水平应用下的动脉血气、氧合指数(PaO2/Fi2)、血压、呼吸频率(R)等进行综合分析。结果:在基础治疗基础上,合理应用PEEP机械通气后7例患者的pH值、二氧化碳分压、PaO2/Fi2、R均较治疗前有明显改善(P0.01),有效率为100%。结论:合理的PEEP水平能有效改善急性重度光气中毒患者的PaO2/Fi2,有利于提高救治率。

Abstract: Objective: To investigate the rational application of the positive end-expiratory pressure(PEEP) mechanical ventilation in severe acute phosgene poisoning.Methods: The data of arterial blood gas,oxygenation index(PaO2/ Fi2),blood pressure,respiratory rate(R) of 7 cases with severe acute phosgene poisoning treated with different PEEP were analysed.Results: The pH value,PaCO2,PaO2/ Fi2 and R of 7 patients were obviously improved after PEEP mechanical ventilation based on the basic treatment(P 0.01),and which efficiency were 100%.Conclusions: The reasonable application of PEEP in patients with severe acute phosgene poisoning can improve oxygenation index and increase cure rate.