Abstract: Objective: To explore the effects of early enteral nutrition(EEN) on the nutritional support of postoperative patients with upper gastrointestinal tract tumor.Methods: Sixty-four and 56 cases with upper gastrointestinal tract tumor were treated with elemental diet through nasointestinal tube(EEN group) and traditional parenteral nutrition(PN group) at 24 h after operation,respectively.The levels of serum albumin(ALB) and prealbumin(PA) in two groups were observed at 1 day before operation and 6 days after operation.The time of the first time postoperative gastrointestinal exhaust,the related complication during the period of early enteral nutrition and postoperative complication were observed.Results: The preoperative levels of ALB and PA in two groups were not statistic significance(P 0.05).The postoperative levels of ALB and PA in two groups decreased obviously,the decreasing degree of PN group was higher than that in EEN group(P 0.01).The time of the first postoperative gastrointestinal exhaust in EEN group was earlier than that in PN group(P 0.01).The incidence of postoperative complication in EEN group(13.4%) was significantly lower than that in PN group(34.2%)(P 0.01).Conclusions: The EEN is safe and effective in the nutritional support of postoperative patients with upper gastrointestinal tract tumor.Promoting the patient gastrointestinal function early recovery and protecting intestinal mucosa normal digest function can reduce the postoperative patient infusion load.