Abstract: Objective:To investigate the the clinic application value of laparoscopic splenectomy(LS).Methods:Thirty-one cases with splenectomy were treated with LS(15 cases) and open splenectomy(OS)(16 cases).The operation time,intraoperative bleeding,postoperative recovery and complications and hospitalization expense of all cases were evaluated.Results:All cases were successfully operated.The length of incision,the time of anal exhaust and out of bed and the hospital stay of LS group were shorter than that of OS group(P0.05 to P0.01),while its hospitalization expense was high(P0.01).The operative time,bleeding loss and complications of two groups were not statistically significant(P0.05).Conclusions:Laparoscopic splenectomy is a safe,feasible,good effects and minimally invasive surgery for most spleen diseases.