Abstract: Objective:To investigate the clinic effects of posterior pedicle fixation system on thoracolumbar fracture.Methods:Sixty patients with thoracolumbar fracture were randomly divided into the observation and control group(30 in each group) according to the surgery serial number.The observation group were treated with posterior pedicle fixation system and the control group were treated with conventional pedicle screw fixation.The heights of anterior and posterior margin of vertebral centrum injuied,Cobb's angle correction,the spinal canal cross-sectional area improved and the spinal nerves injuries of two groups after operation were statistically analyzed.Results:The heights of anterior and posterior margin of vertebral centrum injuried,Cobb's angle,spinal canal cross-sectional area and spinal nerves injuries of two groups were no significantly different(P0.05) at preoperation,and these data were improved to some extent at postoperation and the improvement of the observation were better than that of the control group(P0.05).Conclusions:The clinic effects of treatment of thoracolumbar fracture with posterior pedicle fixation system are good,reliable and less trauma,which is worthy of being widely applied in clinic.