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    张亚军, 汪庚明, 徐洪波, 张雷, 段诗苗, 周育夫, 江浩. 局限期小细胞肺癌预防性脑照射疗效观察[J]. 蚌埠医科大学学报, 2013, 37(9): 1084-1086.
    引用本文: 张亚军, 汪庚明, 徐洪波, 张雷, 段诗苗, 周育夫, 江浩. 局限期小细胞肺癌预防性脑照射疗效观察[J]. 蚌埠医科大学学报, 2013, 37(9): 1084-1086.
    shu
    ZHANG Ya-jun, WANG Geng-ming, XU Hong-bo, ZHANG Lei, DUAN Shi-miao, ZHOU Yu-fu, JIANG Hao. The effect of prophylactic cranial irradiation on limited small cell lung cancer[J]. Journal of Bengbu Medical University, 2013, 37(9): 1084-1086.
    Citation: ZHANG Ya-jun, WANG Geng-ming, XU Hong-bo, ZHANG Lei, DUAN Shi-miao, ZHOU Yu-fu, JIANG Hao. The effect of prophylactic cranial irradiation on limited small cell lung cancer[J]. Journal of Bengbu Medical University, 2013, 37(9): 1084-1086.
    shu

    局限期小细胞肺癌预防性脑照射疗效观察

    The effect of prophylactic cranial irradiation on limited small cell lung cancer

      摘要
    • 摘要: 目的:探讨预防性脑照射(PCI)对完全缓解后的局限期小细胞肺癌(SCLC)脑转移率和生存率的影响。方法:49例经化疗加放疗后完全缓解的局限期SCLC患者随机分为PCI组25例和对照组24例。PCI组患者接受PCI总量为25 Gy;对照组不做PCI。观察2组脑转移率和1、3、5年生存率。结果:PCI组患者的脑转移率为12.0%,对照组为41.7%,2组差异有统计学意义(P0.05)。PCI组患者1、3、5年生存率分别为76.0%、32.0%和20.0%,对照组分别为58.3%、20.8%和12.5%,差异均无统计学意义(P0.05)。结论:PCI能减少局限期SCLC的脑转移。

       

      Abstract: ObjectiveTo evaluate the effects of prophylactic cranial irradiation( PCI) on the survival and brain metastatic rates in patients with limited small-cell lung cancer( SCLC) after complete remission. Methods: Fourty-nine patients with limited SCLC after complete remission treated with chemoradiotherapy were randomly divided into PCI group( 25 cases) and control group( 24 cases) .The PCI group were irradiated at the dose of 25 Gy; the control group didn't receive PCI.The rate of brain metastases and the 1，3，5-year survival rates were assessed.Results: The incidence of brain metastasis of PCI group and control were 12.0% and 41.7%，respectively， the difference of which was statistically significant( P 0.05) .The 1，3 and 5 years survival rates in PCI group were 76.0%， 32.0% and 20.0%，respectively.The 1，3 and 5 years survival rates in control were 58.3%，20.8% and 12.5%，respectively.The differences of survival rates between two groups were not statistically significant( P 0.05) . Conclusions: PCI can decrease the incidence of brain metastasis of patients with limited SCLC.

       

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