徐灼均, 徐宁, 梁映亮, 张杰良, 隋洪. 母婴感染梅毒螺旋体血清学分析[J]. 蚌埠医科大学学报, 2014, 38(2): 255-256.
    引用本文: 徐灼均, 徐宁, 梁映亮, 张杰良, 隋洪. 母婴感染梅毒螺旋体血清学分析[J]. 蚌埠医科大学学报, 2014, 38(2): 255-256.
    Xu Zhuojun, Xu Ning, Liang Yingliang, Zhang Jieliang, Sui Hong. The serological analysis of mothers infected with Treponema pallidum and their newborns[J]. Journal of Bengbu Medical University, 2014, 38(2): 255-256.
    Citation: Xu Zhuojun, Xu Ning, Liang Yingliang, Zhang Jieliang, Sui Hong. The serological analysis of mothers infected with Treponema pallidum and their newborns[J]. Journal of Bengbu Medical University, 2014, 38(2): 255-256.

    母婴感染梅毒螺旋体血清学分析

    The serological analysis of mothers infected with Treponema pallidum and their newborns

    • 摘要: 目的:分析梅毒抗体阳性待产妇及其新生儿的梅毒血清学检测结果,为新生儿梅毒的防治提供参考。方法:对131例梅毒抗体阳性的待产妇及其新生儿使用梅毒快速血浆反应素(RPR)试验和螺旋体抗体明胶颗粒凝集(TPPA)试验进行检测,比较母婴RPR的滴度。结果:131例梅毒抗体阳性的待产妇RPR滴度阳性88例,阴性43例;131例新生儿RPR滴度阳性48例,阴性83例。母婴梅毒滴度等级相关系数为0.857,呈显著正相关关系(P0.01)。结论:梅毒抗体阳性的待产妇RPR滴度越高,新生儿RPR滴度阳性率也越高。临床上对梅毒抗体阳性的产妇应联合检测母婴的RPR和TPPA试验。

       

      Abstract: Objective: To analyze the serum of expectant mothers with positive syphilis antibody and their newborns and provide the basis for preventing neonatal syphilis. Methods: The serum of 131 expectant mothers with positive syphilis antibody and their newborns were detected by rapid plasma reagent RPR(test) and treponema pallidum particle agglutination assay (TPPA). The RPR titer of mothers and their newborns were compared. Results: Among 131 expectant mothers with positive syphilis antibody, the postive RPR titer in 88 cases and negative RPR titer in 43 cases were found. Among 131 newborns, the postive RPR titer in 48 cases and negative RPR titer in 83 cases were found. The correlation coefficient of RPR titer between the expectant mothers and their newborns was 0. 857,which was significantly positive correlation(P < 0. 01). Conclusions: The positive rate of newborns' RPR titer rises with the increasing of RPR titer of expectant mothers with positive syphilis antibody. The detection of RPR combined with TPPA in expectant mothers with positive syphilis antibody and their newborns should be implemented.

       

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