Abstract: Objective:To explore the reasons for misdiagnosis of anxiety disorders as coronary heart disease. Methods:Thirty cases with anxiety disorders misdiagnosed as coronary heart disease were analyzed retrospectively. Results:The patients were relatively young at age(30 to 45); female were more easily affected,accounting for 1.5 times more than the male; most of the victims endured great social and mental pressure. The mark of HAMA after treatment was obviously lower than that before treatment(P<0.01). Six cases recovered completely,18 improved significantly,5 improved and 1 had no response. Conclusions:As anxiety disorders and coronary heart disease present many similar or the same symptoms,it is easy to be misdiagnosed. Besides possessing rich professional knowledge,clinical doctors should ask about the case history of the patients in detail and make comprehensive analysis to decrease the incidence of misdiagnosis.