Abstract: Objective: To improve the molybdenum target radiologic diagnosis rate of breast cancer. Methods: The X-ray findings of 27 patients with breast cancer confirmed by operation and pathology were analyzed. Results: Among 27 patients, lump in 22 patients, calcifications in 13, focal architecture distortion in 5, skin and nipple change in 3, the asymmetrical dilated vessel in 2 and armpit lymphadenovarix in 2 were found. Conclusions: The molybdenum target radiography is very valuable for the diagnosis of breast cancer. More attention should be paid to its application in the field of differential diagnosis.