Abstract: Objective: To evaluate and compare the efficacy of ningmitai-terazosin and prostat in treatment of chronic nonbacterial prostatitis(CNP).Methods: Based on National Institutes of Health(NIH) classification,118 cases of CNP were randomly divided into ningmitai-terazosin group(60 cases) and prostat group(58 cases).The drugs were administered for 8 weeks and the clinical symptoms before and after treatment were surveyed.The chronic prostatitis symptom index(CPSI) of each patient was evaluated.Results: After 8 weeks' treatment,the symptoms of the two groups improved significantly(P<0.01).The difference in CNP was not significant between the two groups(P>0.05).Compared with pretreatment,the difference in the reduction of micturition scores and ache scores was significant between the two groups(P<0.01).Conclusions: Both ningmitai-terazosin and prostat have a positive effect on CNP.Ningmitai-terazosin is more effective in relieving the stimulus of urethra,while prostat can rapidly relieve the pelvic pain.