以HBsAg和HBeAg为筛查指标监控经手术感染HBV的比较

吴飚; 姜旻岚; 杨双旺

以HBsAg和HBeAg为筛查指标监控经手术感染HBV的比较

Comparison of HBsAg and HBeAg as screening index of HBV infection during operation

摘要

摘要: 目的:比较以HBsAg和HBeAg为筛查指标监控的经手术感染HBV的差别。方法:从控制传染源、切断传播途径和保护易感者3个方面比较以HBsAg和HBeAg为筛查指标的经手术感染HBV监控方法的差别。结果:HBV经单层手套传播的感染阈值为10⁵ID/m l,HBsAg阳性者、HBeAg阴性者和HBeAg阳性者的传染性达感染阈值的比率分别为19.23%、3.20%和83.88%,3组差异有统计学意义(P<0.01)。医护人员有效接种乙型肝炎疫苗后,HBV经手术传播的感染阈值为10^8.5ID/m l,0.64% HBsAg阳性者的传染性超过感染阈值,超过者均为HBeAg阳性。结论:以HBsAg和HBeAg为筛查指标的两种监控方法在控制传染源、切断传播途径和保护易感者3个方面都存在差异。

Abstract: Objective:To compare the difference of using HBsAg or HBeAg as screening index of HBV infection during operation.Methods:HBsAg and HBeAg were used as supervising and controlling indexes of HBV infection during operation,and the difference was compared in three aspects:the infective source,the spreading route and the susceptible person.Results:HBV infective threshold value of single layer gloves was 10⁵ ID/ml.The ratio of patients with HBsAg positive,HBeAg negative and HBeAg positive,whose infectivity had reached HBV infective threshold value,were 19.23%,3.20% and 83.88%,respectively.The difference was significant (P<0.01).After healthcare workers were inoculated against HBV,the HBV infective threshold value was 10^8.5 ID/ml during surgical operation;0.64% of the infectious HBsAg positive carriers exceeded the infective threshold value.Conclusions:HBsAg and HBeAg are greatly different as supervising and controlling indexes of HBV infection in infective source,spread route and susceptible person.

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