<sup>131</sup>I治疗甲状腺功能亢进症合并肝功能损害71例疗效观察

¹³¹I治疗甲状腺功能亢进症合并肝功能损害71例疗效观察

摘要: 目的:探讨放射性¹³¹I治疗甲状腺功能亢进症(甲亢)合并肝功能损害的临床价值。方法:对71例甲亢合并肝功能损害患者的临床资料进行回顾性分析。结果:¹³¹I治疗后甲状腺激素水平和肝功能各项指标均明显改善,与治疗前差异均有统计学意义(P<0.05~P<0.01)。治疗后6个月,59例甲亢治愈,61例肝功能完全恢复正常,10例肝功能指标明显下降,5例出现甲状腺功能减退症。结论:¹³¹I是甲亢合并肝功能损害安全有效的治疗方法。

Abstract: Objective:To assess the effect of ¹³¹I therapy on patients with hyperthyroidism complicated with hepatic dysfunction.Methods:Clinical data of 71 cases of hyperthyroidism with liver damage were studied retrospectively.Results:Serum levels of FT3,FT4,aspartate aminotransferase,alanine aminotransferase,alkaline phosphatase,total bilirubin were obviously improved after ¹³¹I treatment (P<0.05 to P<0.01).Of the 71 cases,the liver function of 61 turned normal and 10 showed significant efficacy after 6 months,5 presented with hypothyroidism.Conclusions:¹³¹I is safe and effective in treating hyperthyroidism complicated with hepatic dysfunction.