格拉斯琼对肝动脉化疗栓塞术后消化道症状的临床应用探讨

Granisetron in treatment of complications induced by transcatheter arterial chemoembolization

摘要: 目的: 探讨格拉斯琼对肝动脉化疗栓塞术(TACE)后消化道症状的效果。方法: 44例分二组,分别于术中、术后使用格拉斯琼。结果: 两组患者术后均出现恶心、呕吐、腹胀,但使用格拉斯琼后发生率明显下降(P<0.01)。且愈早使用愈明显。结论: 格拉斯琼对减轻肝癌肝动脉化疗栓塞术后消化道症状的疗效是明显的,认识并尽早使用对患者预后非常重要。

Abstract: Objective: To investigate the effects of granisetron on complications induced by transcatheter arterial chemoembolization(TACE).Methods: Forty-four patients with hepatocellular carcinoma after TACE were divided into 2 groups.The first group used granisetron during the surgery.The second group used granisetron within 24 hours after the surgery.Results: The complications induced by TACE,such as nausea and vomiting,decreased significantly in the first group compared with those in the other group.Conclusions: The effects of granisetron on complications induced by TACE are obvious.Use of granisetron is important for the prognosis of patients with hepatocellular carcinoma after TACE.