Analysis of the irregular antibodies detection in 8 884 patients

Objective:To analyze the blood transfusion results of the patients with irregular antibodies, and provide the basis for avoiding hemolytic reaction.Methods:The antibodies of 8 884 patients were screened using the micro-column gel method, and the specificity of the positive samples were identified with panel cell.Results:Among 8 884 patients, 85 cases with positive irregular antibodies were found, the positive rate of which was 0.96%.The positive rates in male and female were 0.75% (19/2530) and 1.04% (66/6354), respectively.The positive rates in the patients with transfusion history or pregnancy history and without transfusion history and without pregnancy history were 1.17%(70/5980) and 0.52% (15/2904), respectively, the difference of which was statistically significant (P<0.01).Conclusions:The positives rates of irregular antibodies in female and the patients with transfusion history or pregnancy history are higher than that in male and the patients without transfusion history and pregnancy history.The screening of irregular antibody before transfusion can ensure its security.