Correlations of abdominal obesity with atherosclerosis and peripheral arterial disease

Objective: To investigate the correlations of abdominal obesity with atherosclerosis and peripheral arterial disease.Methods: One hundred and eighteen cases from outpatient department of endocrinology department and physical examination people were divided into the abdominal obesityAO group,waist to height ratio(WHtR)more than or equal to 0.5,64 cases and no abdominal obesityl NAO group,WHtR less than 0.5,54 cases) according to the value of WHtR.The correlations of WHtR,and carotid intima-media thickness(CIMT) and ankle-brachial index(ABI) were analyzed.Results: Compared with the NAO group,the body mass index,waist circumference,systolic blood pressure,triglyceride,total cholesterol,low density lipoprtein cholestorol and CIMT in AO group significantly increased(P<0.05 to P<0.01),but their high density lipoprotein cholesferol and ABI levels decreased significantly(P<0.01).Multiple linear regression analysis showed that WHtR was the independent risk factor for CIMT and ABI.Multiple logistic regression analysis showed that the morbidities of atherosclerosis and peripheral arterial disease in AO group were 3.48 times(95%CI=1.389 to 9.941,P<0.01) and 2.27 times(95%CI=1.061 to 3.132,P<0.01) against the NAO group,respectively.Conclusions: The morbidities of atherosclerosis and peripheral arterial disease in people with abdominal obesity are significantly higher than those in people without abdominal obesity.The risk factor of cardiovascular disease should be paid attention to.