Cognitive impairment in chronic obstructive pulmonary disease and its relation to depression、anxiety and BODE index

Objective: To investigate the relationships between cognitive function,depression,anxiety and BODE index(including body mass index,airflow obstruction,dyspnea and exercise capacity index) in patients with chronic obstructive pulmonary disease(COPD).Methods: In the cross-sectional study method,53 patients diagnosed as COPD were evaluated for cognitive function,depression,anxiety and BODE scores,49 normal health controls were evaluated for cognitive function,depression,anxiety scores.The differences of COPD group and control group in cognitive function and depression,anxiety were analyzed.The relationship between cognitive function and depression,anxiety and BODE index in COPD group were analyzed.Results: Compared with control group,cognitive function in COPD group decreased significantly(P<0.01)and the depression and anxiety scores of COPD group all increased significantly(P<0.01).Compared with COPD patients without cognitive impairment,the scores of depression,anxiety and BODE index of COPD patients with cognitive impairment all increased significantly(P<0.01).The cognitive function was negatively correlated with depression,anxiety and BODE index scores in COPD group(P<0.01)Conclusions: Cognitive function and depression,anxiety and BODE index in COPD group were closely related.