Application of the intraoperative autotransfusion in spinal rapid rehabilitation surgery

Objective:To observe the effects of intraoperative autotransfusion on the inflammatory reaction, coagulation function and other complications of spine surgery patients.Methods:Sixty spine surgery patients, whose haemorrhage amount was expected to more than 600 ml, were randomly divided into the autotransfusion group(group A) and allogeneic transfusion group(group B) using a random number table(30 cases in each group).Arterial blood gas analysis, coagulation function and the levels of interleukin-6 and -10(IL-6 and -10) detected by radioimmunoassay in two groups were recorded before transfusion, after 1 h(T₂), 24 h(T₃), 48 h(T₄) and 72 h(T₅) of transfusion.The postoperative infection, wound healing and hospitalization days in two groups were observed after operation.Results:The levels of IL-6 and IL-10 in group A at T₂ to T₅ were significantly lower than those in group B(P<0.01).The differences of Hemoglobin and coagulation function after transfusion between two groups were not statistically significant(P>0.05).Compared with group B, no postoperative transfusion complication, good wound healing and short hospitalization days were found in group A(P<0.01).Conclusions:The intraoperative autotransfusion can obviously reduce the levels of IL-6 and IL-10 and postoperative complication, and promote rapid recovery in spine surgery patients.