Clinical observation of the Narcotrend index in monitoring the depth of sevoflurane inhalation anesthesia

Objective:To observe the changes of Narcotrend index(NTI) during sevoflurane inhalation anesthesia,analyze the clinical significance of monitoring the depth of anesthesia using NTI,and explore the accuracy,sensitivity and stability.Methods:Ninety patients(ASA grade Ⅰ to Ⅱ) scheduled by abdominal surgery under general anesthesia through endotracheal intubation were selected.The vital signs and NTI value in the patients were monitored,all cases inhaled sevoflurane.The endotracheal intubation in the patients were implemented following by intravenous injection of sufentanyl and cisatracurium after the consciousness of patients disappeared.The levels of NTI,mean aortic pressure(MAP),heart rate(HR) and blood glucose(Glu) in all cases were recorded at the beginning of induction(T₀),before incubation(T₁),incubation(T₂),after 3 min of intubation(T₃),after cutting skin(T₄),opening abdomen(T₅),stopping sevoflurane(T₆),before excubation(T₇) and after 5 min of excubation(T₈).Results:The levels of NTI,MAP and HR dropped gradually with the time prolonging of inhaling sevoflurane,which increased after the stimulation of endotracheal intubation,cutting skin,opening abdomen and anesthesia recovery.Compared with T₀,the NTI value at T₁ and T₃ significantly decreased(P<0.01).Compared with T₁,the NTI value at T₂,T₄ and T₃ significantly increased(P<0.01).Conclusions:Narcotrend value can accurately monitor the depth of anesthesia during the sevoflurane anesthesia,which can accurately judge the induction period of anesthesia,surgery and anesthesia recovery period to guide the regulation of anesthesia depth.