Clinical effect of ambroxol in the treatment of secretory otitis media and its influence on the inflammatory mediators in serum and ear fluid

Objective:To observe the clinical effects of ambroxol in the treatment of secretory otitis media, and its influence on the inflammatory mediators in serum and ear fluid.Methods:Seventy-eight patients with secretory otitis media were randomly divided into the control group(treatment with routine method) and observation group(treatment with routine method combined with ambroxol)(39 cases each group).The total effective rates at 1 and 2 weeks after treatment and the levels of inflammatory mediators before and after treatment between two groups were compared.Results:The total effective rates in observation group at 1 and 2 weeks after treatment were higher than those in control group(P<0.05).The levels of inflammatory mediators in observation group after treatment were lower than those in control group(P<0.01).Conclusions:The clinical effect of ambroxol in the treatment of secretory otitis media is good, and its improvement for the inflammatory mediators serum and ear fluid is not obvious, the application value of which in treating secretory otitis media is high.