The application of two-dimensional ultrasound combined with four-dimensional ultrasound in the diagnosis of fetal malformation

Objective:To investigate the clinical value of two-dimensional ultrasound combined with four-dimensional ultrasound in the diagnosis of fetal malformation.Methods:Five thousand and fifty pregnant women detected by two-dimensional ultrasound combined with four-dimensional ultrasound, pregnancy 20 to 28 weeks were investigated.The fetus was examined using two-dimensional ultrasonography, the fetus suspected with malformation was additionally examined using four-dimensional ultrasound.The data of the induced abortion, delivery and further examination results from superior hospital were analyzed to evaluate the diagnosis coincidence rate.Results:Five thousand and sixty-four fetuses(including 14 cases twin) born by five thousand and fifty pregnant women included 87 cases malformation detected by two-dimensional ultrasonography and 117 cases malformation detected by two-dimensional ultrasound combined with four-dimensional ultrasound.The diagnosis coincidence rate of two-dimensional ultrasound combined with four-dimensional ultrasound(94.4%) was significantly higher than that of two-dimensional ultrasound(70.2%)(P<0.01).Conclusions:The two-dimensional ultrasound combined with four-dimensional ultrasound can effectively improve the accurate rate of diagnosis, and reduce the birth rate of defect child, which has high clinical value.